Sesderma Hidraderm TRX Liposomal Mist 100ml is a refreshing, brightening anti-pigmentation facial mist from the Spanish dermatological skincare brand Sesderma. The lightweight liposome-encapsulated formula combines tranexamic acid, niacinamide, hyaluronic acid and tetrahydrocurcumin — to hydrate, brighten and visibly target the appearance of pigmentation and uneven skin tone in a single refreshing spritz.
About Sesderma
Sesderma is a Spanish dermatological skincare brand founded in 1989 by dermatologist Dr Gabriel Serrano in Valencia. The brand pioneered liposome encapsulation in cosmeceutical skincare — a delivery technology that allows actives to penetrate the skin more effectively. The Hidraderm TRX range is the brand's flagship brightening and anti-dark-spot line, built around the renowned tranexamic acid active.
Key actives
- Tranexamic Acid (TRX): the line's hero — a celebrated anti-pigmentation active that targets the appearance of dark spots, uneven tone and melasma-style hyperpigmentation.
- Niacinamide (Vitamin B3): a multi-tasking active that supports a more even, brighter-looking complexion and a healthier-looking skin barrier.
- Tetrahydrodiferuloylmethane (Tetrahydrocurcumin): a stable, refined curcumin derivative — a potent antioxidant that supports a more even skin tone.
- 4-Butylresorcinol: a brightening active that targets the appearance of dark spots.
- Sodium Hyaluronate (Hyaluronic Acid): draws and binds moisture for plumper, hydrated skin.
- Vitamin E (Tocopheryl Acetate): antioxidant protection.
- Liposomal delivery system: supports deeper, more effective penetration of the actives.
Key benefits
- Brightens and visibly evens skin tone.
- Targets the appearance of dark spots, melasma and post-inflammatory hyperpigmentation.
- Hydrates the skin with hyaluronic acid.
- Convenient mist format — easy to apply throughout the day, over makeup if needed.
- Liposome encapsulation supports deeper, more effective active penetration.
- Generous 100ml format — lasts months even with daily use.
Who it's for
Hidraderm TRX Liposomal Mist is for those concerned about dark spots, melasma, uneven skin tone and post-inflammatory hyperpigmentation — particularly post-pregnancy (chloasma), post-acne marks, sun spots and age spots. Particularly well-suited to those who already use Sesderma skincare, or anyone after a clinical-style brightening treatment in a lightweight mist format. A natural pair with the wider Hidraderm TRX range.
How to use
- Use throughout the day — morning, evening, or as a top-up over makeup.
- Shake the bottle gently before use.
- Hold the bottle around 20cm from the face.
- Close the eyes and mist evenly across the face and neck.
- Allow to air-dry — do not wipe off.
- Pair with the wider Hidraderm TRX routine and always wear SPF in the daytime — UV exposure is the leading cause of pigmentation.
Specifications
- Size: 100ml
- Format: Liposomal brightening mist spray
- Range: Hidraderm TRX
- Targets: Dark spots, melasma, uneven tone, hyperpigmentation
- Brand: Sesderma



