Perricone MD Essential Fx Acyl-Glutathione Intensive Overnight Moisturizer 59ml is a high-performance overnight moisturiser from the celebrated American skincare brand Perricone MD. Designed to repair and renew the skin while you sleep, the rich formula is enriched with the brand's signature Acyl-Glutathione complex — for visibly firmer, smoother, more radiant skin by morning.
About Perricone MD Essential Fx
Perricone MD is an American skincare brand founded by celebrated dermatologist Dr Nicholas Perricone, internationally recognised for its science-led, results-driven formulas. The Essential Fx Acyl-Glutathione line is the brand's hero high-performance anti-ageing range — built around the powerful Acyl-Glutathione complex.
Key features
- Targets: fine lines, loss of firmness, dullness
- Hero ingredient: Acyl-Glutathione complex
- Action: repairs and renews overnight
- Texture: rich, comforting overnight moisturiser
- Use: nightly
Who it's for
Best for those with mature skin or visible signs of ageing who want science-led overnight renewal — and a great choice for fans of Perricone MD looking for results-driven anti-ageing skincare.
How to use
- Cleanse and tone the skin in your evening routine.
- Apply your serum if used.
- Warm a small amount of cream between fingertips.
- Massage into face and neck using upward, sweeping motions before bed.
Specifications
- Size: 59ml
- Format: Overnight moisturiser
- Skin type: Mature, all skin types
- Brand: Perricone MD
- Range: Essential Fx Acyl-Glutathione Intensive Overnight Moisturizer
- Use: Nightly

