Peter Thomas Roth Vital-E Microbiome Age Defence Cream 50ml is a high-performance microbiome-supporting age-defence moisturiser from the celebrated American clinical skincare brand Peter Thomas Roth. The advanced formula combines Gamma-E Antioxidant Technology, 3% Butterfly Ginger Root Extract and Fensebiome Peptide — to strengthen the skin's barrier, defend against environmental damage and support overall skin health.
About Peter Thomas Roth
Peter Thomas Roth is an American clinical skincare brand founded in 1993 by Peter Thomas Roth — a third-generation skincare specialist. The brand is celebrated worldwide for its results-driven, clinically-developed formulations and its commitment to advanced skincare science. The Vital-E range is the brand's microbiome-supporting anti-ageing line.
Key actives
- Gamma-E Antioxidant Technology: the brand's proprietary antioxidant complex — defends against environmental damage.
- 3% Butterfly Ginger Root Extract: supports skin barrier strength and resilience.
- Pre/Pro-Biodefense Complex: acts as an "invisible shield" to support the skin's natural barrier and microbiome.
- Fensebiome Peptide: supports microbiome health — the balance of beneficial micro-organisms on the skin.
- Tucumã Butter: a richly nourishing Amazonian butter that improves hydration.
Key benefits
- Strengthens the skin's natural barrier with the Pre/Pro-Biodefense Complex.
- Supports a healthy, balanced microbiome.
- Defends against environmental damage thanks to the Gamma-E Antioxidant Technology.
- Deeply hydrates the skin with Tucumã Butter.
- Visibly improves skin radiance and comfort.
- Clinical-grade quality from a respected American skincare brand.
Who it's for
Peter Thomas Roth Vital-E Microbiome Age Defence Cream is for adults concerned about the visible effects of pollution, urban stress and barrier-compromised skin — particularly those with sensitive, reactive or stressed complexions. The microbiome-supporting approach is especially well-suited to those experiencing the after-effects of harsh products, over-exfoliation or skincare "overuse". A natural pair with the wider Peter Thomas Roth Vital-E routine.
How to use
- Morning and/or evening, after cleansing, toning and applying any serum.
- Dispense a hazelnut-sized amount onto the fingertips.
- Apply across the face and neck in upward, outward strokes.
- Massage gently for 20–30 seconds.
- Allow to absorb before applying sun protection and/or makeup.
- Always wear SPF in daytime — UV exposure is the leading cause of skin barrier damage.
Specifications
- Size: 50ml
- Format: Microbiome-supporting age-defence cream
- Range: Vital-E
- Targets: Barrier weakness, environmental stress, dullness
- Brand: Peter Thomas Roth



