Sesderma Acglicolic 20 Moisturizing Gel Cream 50ml is the higher-strength version of the Spanish brand's flagship glycolic-acid skincare range, formulated with 15% free and liposomal glycolic acid. The multi-action gel cream combines daily moisturisation with serious resurfacing power — designed to smooth fine lines, refine pores, even skin tone and visibly brighten dull complexions, supported by sea-holly stem cells, vitamins C and E, and ergothioneine.
About Sesderma Acglicolic
Sesderma is a Spanish dermatological skincare brand founded in 1989, recognised internationally for its pioneering use of liposome technology in cosmetic skincare. The Acglicolic range is one of the brand's flagship lines, built entirely around glycolic acid — with Acglicolic 20 sitting as the highest-strength daily product in the family, designed for skin already accustomed to AHA exfoliation.
Key ingredients
- 15% Free and Liposomal Glycolic Acid — high-strength AHA, partly delivered in liposome form for more gradual penetration; smooths texture and resurfaces.
- Sea Holly (Eryngium Maritimum) Stem Cells — supports skin firmness and elasticity.
- Ergothioneine — antioxidant amino acid that helps protect against free-radical damage.
- Vitamins C and E — antioxidant brightening and protection.
- Aloe Vera and Bisabolol — soothing and calming botanicals.
- Natural Moisturising Factor — supports the skin's own hydration mechanism.
- Allantoin and Hydrolysed Collagen — supporting conditioning agents.
Key benefits
- Reduces the appearance of fine lines and wrinkles
- Refines the look of pores and skin texture
- Brightens dull, uneven complexions
- Hydrates and conditions while exfoliating
- Helps even out the appearance of skin tone
- Gel-cream texture absorbs quickly
Who it's for
Specifically formulated for skin already accustomed to glycolic acid skincare — not recommended as a first introduction to AHAs. Best suited to women in their 30s and beyond dealing with multiple signs of ageing — dullness, fine lines, pores, uneven tone — across normal and combination skin. Patch test first if you have sensitive skin.
How to use
- Cleanse the face thoroughly and pat dry.
- Take a hazelnut-sized amount of gel cream and warm between the fingertips.
- Smooth across the face and neck in upward, outward strokes, avoiding the immediate eye area.
- For evening use (recommended given the high glycolic content).
- For morning use, follow strictly with a broad-spectrum sunscreen — AHA skincare significantly increases sensitivity to UV.
- If the formula causes any irritation, reduce frequency or pair with a barrier-soothing routine.
Specifications
- Size: 50ml
- Format: Anti-ageing gel cream moisturiser
- Brand: Sesderma (Spain)
- Range: Acglicolic 20
- Key active: 15% Free and Liposomal Glycolic Acid
- Suitable for: Normal and combination skin already accustomed to glycolic acid



